Krizové řízení pandemie/Biologická Kryptografie/Genetický kód v binární soustavě

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Jak používat klasifikační nálepkuTato stránka je součástí projektu:
Příslušnost: všeobecná

Stránka je součástí výzkumu "Krizového řízení pandemie" a je vnořeným podprojektem Biologické Kryptografie.

Úvod[editovat]

Převod genetického kódu DNA do binární soustavy[editovat]

Teorie[editovat]

Váží se spolu vždy jen 2 specifické N-báze (vždy 1 báze pyrimidinová a 1 purinová), a to:

  • A - T proto 00 - 01 čímž vytváří první znak třídu 0
  • G - C proto 10 - 11 čímž vytváří první znak třídu 1

Struktura je tvořena třemi složkami – cukr, fosfát, báze. Cukernou složku tvoří pěti uhlíkový cukr 2-deoxy-D-ribosa (oproti normální ribóze u DNA v poloze 2' chybí kyslík). Jakožto dusíkaté báze jsou v DNA zastoupeny deriváty purinu (A - Adenin, G - Guanin) a deriváty pyrimidinu (C - Cytosin, T - Thymin). Mezi N-bázemi protějších vláken dochází k vazebným interakcím. Kde dvojce A=T má dvojitou vazbu a G≡C trojitou vazbu.

Program v Pythonu[editovat]

Základní myšlenky[editovat]

 1 sekvence = "gttctctaaa cgaactttaa aatctgtgtg gctgtcactc ggctgcatgc ttagtgcact"
 2 
 3 b = ""
 4 for x in sekvence:
 5     if x == "a":
 6         y = "00"
 7     elif x == "t":
 8         y = "01"
 9     elif x == "g":
10         y = "10"
11     elif x == "c":
12         y = "11"
13     elif x == " ":
14         y = " "
15     b = b + y
16 print(b)

výstup:
10010111011101000000 11100000110101010000 00000111011001100110 10110110011100110111 10101101101100011011 01010010011011001101

Převod celého kódu genomu bez mezer[editovat]

  • převod genomu na formu bez mezer a znaků zalomení řádků a čísel aby vznikl souvislí jednořádkový text
  • odstraněny byli tedy následující znaky " \n0123456789"
  1 cc = """1 attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct
  2        61 gttctctaaa cgaactttaa aatctgtgtg gctgtcactc ggctgcatgc ttagtgcact
  3       121 cacgcagtat aattaataac taattactgt cgttgacagg acacgagtaa ctcgtctatc
  4       181 ttctgcaggc tgcttacggt ttcgtccgtg ttgcagccga tcatcagcac atctaggttt
  5       241 cgtccgggtg tgaccgaaag gtaagatgga gagccttgtc cctggtttca acgagaaaac
  6       301 acacgtccaa ctcagtttgc ctgttttaca ggttcgcgac gtgctcgtac gtggctttgg
  7       361 agactccgtg gaggaggtct tatcagaggc acgtcaacat cttaaagatg gcacttgtgg
  8       421 cttagtagaa gttgaaaaag gcgttttgcc tcaacttgaa cagccctatg tgttcatcaa
  9       481 acgttcggat gctcgaactg cacctcatgg tcatgttatg gttgagctgg tagcagaact
 10       541 cgaaggcatt cagtacggtc gtagtggtga gacacttggt gtccttgtcc ctcatgtggg
 11       601 cgaaatacca gtggcttacc gcaaggttct tcttcgtaag aacggtaata aaggagctgg
 12       661 tggccatagt tacggcgccg atctaaagtc atttgactta ggcgacgagc ttggcactga
 13       721 tccttatgaa gattttcaag aaaactggaa cactaaacat agcagtggtg ttacccgtga
 14       781 actcatgcgt gagcttaacg gaggggcata cactcgctat gtcgataaca acttctgtgg
 15       841 ccctgatggc taccctcttg agtgcattaa agaccttcta gcacgtgctg gtaaagcttc
 16       901 atgcactttg tccgaacaac tggactttat tgacactaag aggggtgtat actgctgccg
 17       961 tgaacatgag catgaaattg cttggtacac ggaacgttct gaaaagagct atgaattgca
 18      1021 gacacctttt gaaattaaat tggcaaagaa atttgacacc ttcaatgggg aatgtccaaa
 19      1081 ttttgtattt cccttaaatt ccataatcaa gactattcaa ccaagggttg aaaagaaaaa
 20      1141 gcttgatggc tttatgggta gaattcgatc tgtctatcca gttgcgtcac caaatgaatg
 21      1201 caaccaaatg tgcctttcaa ctctcatgaa gtgtgatcat tgtggtgaaa cttcatggca
 22      1261 gacgggcgat tttgttaaag ccacttgcga attttgtggc actgagaatt tgactaaaga
 23      1321 aggtgccact acttgtggtt acttacccca aaatgctgtt gttaaaattt attgtccagc
 24      1381 atgtcacaat tcagaagtag gacctgagca tagtcttgcc gaataccata atgaatctgg
 25      1441 cttgaaaacc attcttcgta agggtggtcg cactattgcc tttggaggct gtgtgttctc
 26      1501 ttatgttggt tgccataaca agtgtgccta ttgggttcca cgtgctagcg ctaacatagg
 27      1561 ttgtaaccat acaggtgttg ttggagaagg ttccgaaggt cttaatgaca accttcttga
 28      1621 aatactccaa aaagagaaag tcaacatcaa tattgttggt gactttaaac ttaatgaaga
 29      1681 gatcgccatt attttggcat ctttttctgc ttccacaagt gcttttgtgg aaactgtgaa
 30      1741 aggtttggat tataaagcat tcaaacaaat tgttgaatcc tgtggtaatt ttaaagttac
 31      1801 aaaaggaaaa gctaaaaaag gtgcctggaa tattggtgaa cagaaatcaa tactgagtcc
 32      1861 tctttatgca tttgcatcag aggctgctcg tgttgtacga tcaattttct cccgcactct
 33      1921 tgaaactgct caaaattctg tgcgtgtttt acagaaggcc gctataacaa tactagatgg
 34      1981 aatttcacag tattcactga gactcattga tgctatgatg ttcacatctg atttggctac
 35      2041 taacaatcta gttgtaatgg cctacattac aggtggtgtt gttcagttga cttcgcagtg
 36      2101 gctaactaac atctttggca ctgtttatga aaaactcaaa cccgtccttg attggcttga
 37      2161 agagaagttt aaggaaggtg tagagtttct tagagacggt tgggaaattg ttaaatttat
 38      2221 ctcaacctgt gcttgtgaaa ttgtcggtgg acaaattgtc acctgtgcaa aggaaattaa
 39      2281 ggagagtgtt cagacattct ttaagcttgt aaataaattt ttggctttgt gtgctgactc
 40      2341 tatcattatt ggtggagcta aacttaaagc cttgaattta ggtgaaacat ttgtcacgca
 41      2401 ctcaaaggga ttgtacagaa agtgtgttaa atccagagaa gaaactggcc tactcatgcc
 42      2461 tctaaaagcc ccaaaagaaa ttatcttctt agagggagaa acacttccca cagaagtgtt
 43      2521 aacagaggaa gttgtcttga aaactggtga tttacaacca ttagaacaac ctactagtga
 44      2581 agctgttgaa gctccattgg ttggtacacc agtttgtatt aacgggctta tgttgctcga
 45      2641 aatcaaagac acagaaaagt actgtgccct tgcacctaat atgatggtaa caaacaatac
 46      2701 cttcacactc aaaggcggtg caccaacaaa ggttactttt ggtgatgaca ctgtgataga
 47      2761 agtgcaaggt tacaagagtg tgaatatcac ttttgaactt gatgaaagga ttgataaagt
 48      2821 acttaatgag aagtgctctg cctatacagt tgaactcggt acagaagtaa atgagttcgc
 49      2881 ctgtgttgtg gcagatgctg tcataaaaac tttgcaacca gtatctgaat tacttacacc
 50      2941 actgggcatt gatttagatg agtggagtat ggctacatac tacttatttg atgagtctgg
 51      3001 tgagtttaaa ttggcttcac atatgtattg ttctttctac cctccagatg aggatgaaga
 52      3061 agaaggtgat tgtgaagaag aagagtttga gccatcaact caatatgagt atggtactga
 53      3121 agatgattac caaggtaaac ctttggaatt tggtgccact tctgctgctc ttcaacctga
 54      3181 agaagagcaa gaagaagatt ggttagatga tgatagtcaa caaactgttg gtcaacaaga
 55      3241 cggcagtgag gacaatcaga caactactat tcaaacaatt gttgaggttc aacctcaatt
 56      3301 agagatggaa cttacaccag ttgttcagac tattgaagtg aatagtttta gtggttattt
 57      3361 aaaacttact gacaatgtat acattaaaaa tgcagacatt gtggaagaag ctaaaaaggt
 58      3421 aaaaccaaca gtggttgtta atgcagccaa tgtttacctt aaacatggag gaggtgttgc
 59      3481 aggagcctta aataaggcta ctaacaatgc catgcaagtt gaatctgatg attacatagc
 60      3541 tactaatgga ccacttaaag tgggtggtag ttgtgtttta agcggacaca atcttgctaa
 61      3601 acactgtctt catgttgtcg gcccaaatgt taacaaaggt gaagacattc aacttcttaa
 62      3661 gagtgcttat gaaaatttta atcagcacga agttctactt gcaccattat tatcagctgg
 63      3721 tatttttggt gctgacccta tacattcttt aagagtttgt gtagatactg ttcgcacaaa
 64      3781 tgtctactta gctgtctttg ataaaaatct ctatgacaaa cttgtttcaa gctttttgga
 65      3841 aatgaagagt gaaaagcaag ttgaacaaaa gatcgctgag attcctaaag aggaagttaa
 66      3901 gccatttata actgaaagta aaccttcagt tgaacagaga aaacaagatg ataagaaaat
 67      3961 caaagcttgt gttgaagaag ttacaacaac tctggaagaa actaagttcc tcacagaaaa
 68      4021 cttgttactt tatattgaca ttaatggcaa tcttcatcca gattctgcca ctcttgttag
 69      4081 tgacattgac atcactttct taaagaaaga tgctccatat atagtgggtg atgttgttca
 70      4141 agagggtgtt ttaactgctg tggttatacc tactaaaaag gctggtggca ctactgaaat
 71      4201 gctagcgaaa gctttgagaa aagtgccaac agacaattat ataaccactt acccgggtca
 72      4261 gggtttaaat ggttacactg tagaggaggc aaagacagtg cttaaaaagt gtaaaagtgc
 73      4321 cttttacatt ctaccatcta ttatctctaa tgagaagcaa gaaattcttg gaactgtttc
 74      4381 ttggaatttg cgagaaatgc ttgcacatgc agaagaaaca cgcaaattaa tgcctgtctg
 75      4441 tgtggaaact aaagccatag tttcaactat acagcgtaaa tataagggta ttaaaataca
 76      4501 agagggtgtg gttgattatg gtgctagatt ttacttttac accagtaaaa caactgtagc
 77      4561 gtcacttatc aacacactta acgatctaaa tgaaactctt gttacaatgc cacttggcta
 78      4621 tgtaacacat ggcttaaatt tggaagaagc tgctcggtat atgagatctc tcaaagtgcc
 79      4681 agctacagtt tctgtttctt cacctgatgc tgttacagcg tataatggtt atcttacttc
 80      4741 ttcttctaaa acacctgaag aacattttat tgaaaccatc tcacttgctg gttcctataa
 81      4801 agattggtcc tattctggac aatctacaca actaggtata gaatttctta agagaggtga
 82      4861 taaaagtgta tattacacta gtaatcctac cacattccac ctagatggtg aagttatcac
 83      4921 ctttgacaat cttaagacac ttctttcttt gagagaagtg aggactatta aggtgtttac
 84      4981 aacagtagac aacattaacc tccacacgca agttgtggac atgtcaatga catatggaca
 85      5041 acagtttggt ccaacttatt tggatggagc tgatgttact aaaataaaac ctcataattc
 86      5101 acatgaaggt aaaacatttt atgttttacc taatgatgac actctacgtg ttgaggcttt
 87      5161 tgagtactac cacacaactg atcctagttt tctgggtagg tacatgtcag cattaaatca
 88      5221 cactaaaaag tggaaatacc cacaagttaa tggtttaact tctattaaat gggcagataa
 89      5281 caactgttat cttgccactg cattgttaac actccaacaa atagagttga agtttaatcc
 90      5341 acctgctcta caagatgctt attacagagc aagggctggt gaagctgcta acttttgtgc
 91      5401 acttatctta gcctactgta ataagacagt aggtgagtta ggtgatgtta gagaaacaat
 92      5461 gagttacttg tttcaacatg ccaatttaga ttcttgcaaa agagtcttga acgtggtgtg
 93      5521 taaaacttgt ggacaacagc agacaaccct taagggtgta gaagctgtta tgtacatggg
 94      5581 cacactttct tatgaacaat ttaagaaagg tgttcagata ccttgtacgt gtggtaaaca
 95      5641 agctacaaaa tatctagtac aacaggagtc accttttgtt atgatgtcag caccacctgc
 96      5701 tcagtatgaa cttaagcatg gtacatttac ttgtgctagt gagtacactg gtaattacca
 97      5761 gtgtggtcac tataaacata taacttctaa agaaactttg tattgcatag acggtgcttt
 98      5821 acttacaaag tcctcagaat acaaaggtcc tattacggat gttttctaca aagaaaacag
 99      5881 ttacacaaca accataaaac cagttactta taaattggat ggtgttgttt gtacagaaat
100      5941 tgaccctaag ttggacaatt attataagaa agacaattct tatttcacag agcaaccaat
101      6001 tgatcttgta ccaaaccaac catatccaaa cgcaagcttc gataatttta agtttgtatg
102      6061 tgataatatc aaatttgctg atgatttaaa ccagttaact ggttataaga aacctgcttc
103      6121 aagagagctt aaagttacat ttttccctga cttaaatggt gatgtggtgg ctattgatta
104      6181 taaacactac acaccctctt ttaagaaagg agctaaattg ttacataaac ctattgtttg
105      6241 gcatgttaac aatgcaacta ataaagccac gtataaacca aatacctggt gtatacgttg
106      6301 tctttggagc acaaaaccag ttgaaacatc aaattcgttt gatgtactga agtcagagga
107      6361 cgcgcaggga atggataatc ttgcctgcga agatctaaaa ccagtctctg aagaagtagt
108      6421 ggaaaatcct accatacaga aagacgttct tgagtgtaat gtgaaaacta ccgaagttgt
109      6481 aggagacatt atacttaaac cagcaaataa tagtttaaaa attacagaag aggttggcca
110      6541 cacagatcta atggctgctt atgtagacaa ttctagtctt actattaaga aacctaatga
111      6601 attatctaga gtattaggtt tgaaaaccct tgctactcat ggtttagctg ctgttaatag
112      6661 tgtcccttgg gatactatag ctaattatgc taagcctttt cttaacaaag ttgttagtac
113      6721 aactactaac atagttacac ggtgtttaaa ccgtgtttgt actaattata tgccttattt
114      6781 ctttacttta ttgctacaat tgtgtacttt tactagaagt acaaattcta gaattaaagc
115      6841 atctatgccg actactatag caaagaatac tgttaagagt gtcggtaaat tttgtctaga
116      6901 ggcttcattt aattatttga agtcacctaa tttttctaaa ctgataaata ttataatttg
117      6961 gtttttacta ttaagtgttt gcctaggttc tttaatctac tcaaccgctg ctttaggtgt
118      7021 tttaatgtct aatttaggca tgccttctta ctgtactggt tacagagaag gctatttgaa
119      7081 ctctactaat gtcactattg caacctactg tactggttct ataccttgta gtgtttgtct
120      7141 tagtggttta gattctttag acacctatcc ttctttagaa actatacaaa ttaccatttc
121      7201 atcttttaaa tgggatttaa ctgcttttgg cttagttgca gagtggtttt tggcatatat
122      7261 tcttttcact aggtttttct atgtacttgg attggctgca atcatgcaat tgtttttcag
123      7321 ctattttgca gtacatttta ttagtaattc ttggcttatg tggttaataa ttaatcttgt
124      7381 acaaatggcc ccgatttcag ctatggttag aatgtacatc ttctttgcat cattttatta
125      7441 tgtatggaaa agttatgtgc atgttgtaga cggttgtaat tcatcaactt gtatgatgtg
126      7501 ttacaaacgt aatagagcaa caagagtcga atgtacaact attgttaatg gtgttagaag
127      7561 gtccttttat gtctatgcta atggaggtaa aggcttttgc aaactacaca attggaattg
128      7621 tgttaattgt gatacattct gtgctggtag tacatttatt agtgatgaag ttgcgagaga
129      7681 cttgtcacta cagtttaaaa gaccaataaa tcctactgac cagtcttctt acatcgttga
130      7741 tagtgttaca gtgaagaatg gttccatcca tctttacttt gataaagctg gtcaaaagac
131      7801 ttatgaaaga cattctctct ctcattttgt taacttagac aacctgagag ctaataacac
132      7861 taaaggttca ttgcctatta atgttatagt ttttgatggt aaatcaaaat gtgaagaatc
133      7921 atctgcaaaa tcagcgtctg tttactacag tcagcttatg tgtcaaccta tactgttact
134      7981 agatcaggca ttagtgtctg atgttggtga tagtgcggaa gttgcagtta aaatgtttga
135      8041 tgcttacgtt aatacgtttt catcaacttt taacgtacca atggaaaaac tcaaaacact
136      8101 agttgcaact gcagaagctg aacttgcaaa gaatgtgtcc ttagacaatg tcttatctac
137      8161 ttttatttca gcagctcggc aagggtttgt tgattcagat gtagaaacta aagatgttgt
138      8221 tgaatgtctt aaattgtcac atcaatctga catagaagtt actggcgata gttgtaataa
139      8281 ctatatgctc acctataaca aagttgaaaa catgacaccc cgtgaccttg gtgcttgtat
140      8341 tgactgtagt gcgcgtcata ttaatgcgca ggtagcaaaa agtcacaaca ttgctttgat
141      8401 atggaacgtt aaagatttca tgtcattgtc tgaacaacta cgaaaacaaa tacgtagtgc
142      8461 tgctaaaaag aataacttac cttttaagtt gacatgtgca actactagac aagttgttaa
143      8521 tgttgtaaca acaaagatag cacttaaggg tggtaaaatt gttaataatt ggttgaagca
144      8581 gttaattaaa gttacacttg tgttcctttt tgttgctgct attttctatt taataacacc
145      8641 tgttcatgtc atgtctaaac atactgactt ttcaagtgaa atcataggat acaaggctat
146      8701 tgatggtggt gtcactcgtg acatagcatc tacagatact tgttttgcta acaaacatgc
147      8761 tgattttgac acatggttta gccagcgtgg tggtagttat actaatgaca aagcttgccc
148      8821 attgattgct gcagtcataa caagagaagt gggttttgtc gtgcctggtt tgcctggcac
149      8881 gatattacgc acaactaatg gtgacttttt gcatttctta cctagagttt ttagtgcagt
150      8941 tggtaacatc tgttacacac catcaaaact tatagagtac actgactttg caacatcagc
151      9001 ttgtgttttg gctgctgaat gtacaatttt taaagatgct tctggtaagc cagtaccata
152      9061 ttgttatgat accaatgtac tagaaggttc tgttgcttat gaaagtttac gccctgacac
153      9121 acgttatgtg ctcatggatg gctctattat tcaatttcct aacacctacc ttgaaggttc
154      9181 tgttagagtg gtaacaactt ttgattctga gtactgtagg cacggcactt gtgaaagatc
155      9241 agaagctggt gtttgtgtat ctactagtgg tagatgggta cttaacaatg attattacag
156      9301 atctttacca ggagttttct gtggtgtaga tgctgtaaat ttacttacta atatgtttac
157      9361 accactaatt caacctattg gtgctttgga catatcagca tctatagtag ctggtggtat
158      9421 tgtagctatc gtagtaacat gccttgccta ctattttatg aggtttagaa gagcttttgg
159      9481 tgaatacagt catgtagttg cctttaatac tttactattc cttatgtcat tcactgtact
160      9541 ctgtttaaca ccagtttact cattcttacc tggtgtttat tctgttattt acttgtactt
161      9601 gacattttat cttactaatg atgtttcttt tttagcacat attcagtgga tggttatgtt
162      9661 cacaccttta gtacctttct ggataacaat tgcttatatc atttgtattt ccacaaagca
163      9721 tttctattgg ttctttagta attacctaaa gagacgtgta gtctttaatg gtgtttcctt
164      9781 tagtactttt gaagaagctg cgctgtgcac ctttttgtta aataaagaaa tgtatctaaa
165      9841 gttgcgtagt gatgtgctat tacctcttac gcaatataat agatacttag ctctttataa
166      9901 taagtacaag tattttagtg gagcaatgga tacaactagc tacagagaag ctgcttgttg
167      9961 tcatctcgca aaggctctca atgacttcag taactcaggt tctgatgttc tttaccaacc
168     10021 accacaaacc tctatcacct cagctgtttt gcagagtggt tttagaaaaa tggcattccc
169     10081 atctggtaaa gttgagggtt gtatggtaca agtaacttgt ggtacaacta cacttaacgg
170     10141 tctttggctt gatgacgtag tttactgtcc aagacatgtg atctgcacct ctgaagacat
171     10201 gcttaaccct aattatgaag atttactcat tcgtaagtct aatcataatt tcttggtaca
172     10261 ggctggtaat gttcaactca gggttattgg acattctatg caaaattgtg tacttaagct
173     10321 taaggttgat acagccaatc ctaagacacc taagtataag tttgttcgca ttcaaccagg
174     10381 acagactttt tcagtgttag cttgttacaa tggttcacca tctggtgttt accaatgtgc
175     10441 tatgaggccc aatttcacta ttaagggttc attccttaat ggttcatgtg gtagtgttgg
176     10501 ttttaacata gattatgact gtgtctcttt ttgttacatg caccatatgg aattaccaac
177     10561 tggagttcat gctggcacag acttagaagg taacttttat ggaccttttg ttgacaggca
178     10621 aacagcacaa gcagctggta cggacacaac tattacagtt aatgttttag cttggttgta
179     10681 cgctgctgtt ataaatggag acaggtggtt tctcaatcga tttaccacaa ctcttaatga
180     10741 ctttaacctt gtggctatga agtacaatta tgaacctcta acacaagacc atgttgacat
181     10801 actaggacct ctttctgctc aaactggaat tgccgtttta gatatgtgtg cttcattaaa
182     10861 agaattactg caaaatggta tgaatggacg taccatattg ggtagtgctt tattagaaga
183     10921 tgaatttaca ccttttgatg ttgttagaca atgctcaggt gttactttcc aaagtgcagt
184     10981 gaaaagaaca atcaagggta cacaccactg gttgttactc acaattttga cttcactttt
185     11041 agttttagtc cagagtactc aatggtcttt gttctttttt ttgtatgaaa atgccttttt
186     11101 accttttgct atgggtatta ttgctatgtc tgcttttgca atgatgtttg tcaaacataa
187     11161 gcatgcattt ctctgtttgt ttttgttacc ttctcttgcc actgtagctt attttaatat
188     11221 ggtctatatg cctgctagtt gggtgatgcg tattatgaca tggttggata tggttgatac
189     11281 tagtttgtct ggttttaagc taaaagactg tgttatgtat gcatcagctg tagtgttact
190     11341 aatccttatg acagcaagaa ctgtgtatga tgatggtgct aggagagtgt ggacacttat
191     11401 gaatgtcttg acactcgttt ataaagttta ttatggtaat gctttagatc aagccatttc
192     11461 catgtgggct cttataatct ctgttacttc taactactca ggtgtagtta caactgtcat
193     11521 gtttttggcc agaggtattg tttttatgtg tgttgagtat tgccctattt tcttcataac
194     11581 tggtaataca cttcagtgta taatgctagt ttattgtttc ttaggctatt tttgtacttg
195     11641 ttactttggc ctcttttgtt tactcaaccg ctactttaga ctgactcttg gtgtttatga
196     11701 ttacttagtt tctacacagg agtttagata tatgaattca cagggactac tcccacccaa
197     11761 gaatagcata gatgccttca aactcaacat taaattgttg ggtgttggtg gcaaaccttg
198     11821 tatcaaagta gccactgtac agtctaaaat gtcagatgta aagtgcacat cagtagtctt
199     11881 actctcagtt ttgcaacaac tcagagtaga atcatcatct aaattgtggg ctcaatgtgt
200     11941 ccagttacac aatgacattc tcttagctaa agatactact gaagcctttg aaaaaatggt
201     12001 ttcactactt tctgttttgc tttccatgca gggtgctgta gacataaaca agctttgtga
202     12061 agaaatgctg gacaacaggg caaccttaca agctatagcc tcagagttta gttcccttcc
203     12121 atcatatgca gcttttgcta ctgctcaaga agcttatgag caggctgttg ctaatggtga
204     12181 ttctgaagtt gttcttaaaa agttgaagaa gtctttgaat gtggctaaat ctgaatttga
205     12241 ccgtgatgca gccatgcaac gtaagttgga aaagatggct gatcaagcta tgacccaaat
206     12301 gtataaacag gctagatctg aggacaagag ggcaaaagtt actagtgcta tgcagacaat
207     12361 gcttttcact atgcttagaa agttggataa tgatgcactc aacaacatta tcaacaatgc
208     12421 aagagatggt tgtgttccct tgaacataat acctcttaca acagcagcca aactaatggt
209     12481 tgtcatacca gactataaca catataaaaa tacgtgtgat ggtacaacat ttacttatgc
210     12541 atcagcattg tgggaaatcc aacaggttgt agatgcagat agtaaaattg ttcaacttag
211     12601 tgaaattagt atggacaatt cacctaattt agcatggcct cttattgtaa cagctttaag
212     12661 ggccaattct gctgtcaaat tacagaataa tgagcttagt cctgttgcac tacgacagat
213     12721 gtcttgtgct gccggtacta cacaaactgc ttgcactgat gacaatgcgt tagcttacta
214     12781 caacacaaca aagggaggta ggtttgtact tgcactgtta tccgatttac aggatttgaa
215     12841 atgggctaga ttccctaaga gtgatggaac tggtactatc tatacagaac tggaaccacc
216     12901 ttgtaggttt gttacagaca cacctaaagg tcctaaagtg aagtatttat actttattaa
217     12961 aggattaaac aacctaaata gaggtatggt acttggtagt ttagctgcca cagtacgtct
218     13021 acaagctggt aatgcaacag aagtgcctgc caattcaact gtattatctt tctgtgcttt
219     13081 tgctgtagat gctgctaaag cttacaaaga ttatctagct agtgggggac aaccaatcac
220     13141 taattgtgtt aagatgttgt gtacacacac tggtactggt caggcaataa cagttacacc
221     13201 ggaagccaat atggatcaag aatcctttgg tggtgcatcg tgttgtctgt actgccgttg
222     13261 ccacatagat catccaaatc ctaaaggatt ttgtgactta aaaggtaagt atgtacaaat
223     13321 acctacaact tgtgctaatg accctgtggg ttttacactt aaaaacacag tctgtaccgt
224     13381 ctgcggtatg tggaaaggtt atggctgtag ttgtgatcaa ctccgcgaac ccatgcttca
225     13441 gtcagctgat gcacaatcgt ttttaaacgg gtttgcggtg taagtgcagc ccgtcttaca
226     13501 ccgtgcggca caggcactag tactgatgtc gtatacaggg cttttgacat ctacaatgat
227     13561 aaagtagctg gttttgctaa attcctaaaa actaattgtt gtcgcttcca agaaaaggac
228     13621 gaagatgaca atttaattga ttcttacttt gtagttaaga gacacacttt ctctaactac
229     13681 caacatgaag aaacaattta taatttactt aaggattgtc cagctgttgc taaacatgac
230     13741 ttctttaagt ttagaataga cggtgacatg gtaccacata tatcacgtca acgtcttact
231     13801 aaatacacaa tggcagacct cgtctatgct ttaaggcatt ttgatgaagg taattgtgac
232     13861 acattaaaag aaatacttgt cacatacaat tgttgtgatg atgattattt caataaaaag
233     13921 gactggtatg attttgtaga aaacccagat atattacgcg tatacgccaa cttaggtgaa
234     13981 cgtgtacgcc aagctttgtt aaaaacagta caattctgtg atgccatgcg aaatgctggt
235     14041 attgttggtg tactgacatt agataatcaa gatctcaatg gtaactggta tgatttcggt
236     14101 gatttcatac aaaccacgcc aggtagtgga gttcctgttg tagattctta ttattcattg
237     14161 ttaatgccta tattaacctt gaccagggct ttaactgcag agtcacatgt tgacactgac
238     14221 ttaacaaagc cttacattaa gtgggatttg ttaaaatatg acttcacgga agagaggtta
239     14281 aaactctttg accgttattt taaatattgg gatcagacat accacccaaa ttgtgttaac
240     14341 tgtttggatg acagatgcat tctgcattgt gcaaacttta atgttttatt ctctacagtg
241     14401 ttcccaccta caagttttgg accactagtg agaaaaatat ttgttgatgg tgttccattt
242     14461 gtagtttcaa ctggatacca cttcagagag ctaggtgttg tacataatca ggatgtaaac
243     14521 ttacatagct ctagacttag ttttaaggaa ttacttgtgt atgctgctga ccctgctatg
244     14581 cacgctgctt ctggtaatct attactagat aaacgcacta cgtgcttttc agtagctgca
245     14641 cttactaaca atgttgcttt tcaaactgtc aaacccggta attttaacaa agacttctat
246     14701 gactttgctg tgtctaaggg tttctttaag gaaggaagtt ctgttgaatt aaaacacttc
247     14761 ttctttgctc aggatggtaa tgctgctatc agcgattatg actactatcg ttataatcta
248     14821 ccaacaatgt gtgatatcag acaactacta tttgtagttg aagttgttga taagtacttt
249     14881 gattgttacg atggtggctg tattaatgct aaccaagtca tcgtcaacaa cctagacaaa
250     14941 tcagctggtt ttccatttaa taaatggggt aaggctagac tttattatga ttcaatgagt
251     15001 tatgaggatc aagatgcact tttcgcatat acaaaacgta atgtcatccc tactataact
252     15061 caaatgaatc ttaagtatgc cattagtgca aagaatagag ctcgcaccgt agctggtgtc
253     15121 tctatctgta gtactatgac caatagacag tttcatcaaa aattattgaa atcaatagcc
254     15181 gccactagag gagctactgt agtaattgga acaagcaaat tctatggtgg ttggcacaac
255     15241 atgttaaaaa ctgtttatag tgatgtagaa aaccctcacc ttatgggttg ggattatcct
256     15301 aaatgtgata gagccatgcc taacatgctt agaattatgg cctcacttgt tcttgctcgc
257     15361 aaacatacaa cgtgttgtag cttgtcacac cgtttctata gattagctaa tgagtgtgct
258     15421 caagtattga gtgaaatggt catgtgtggc ggttcactat atgttaaacc aggtggaacc
259     15481 tcatcaggag atgccacaac tgcttatgct aatagtgttt ttaacatttg tcaagctgtc
260     15541 acggccaatg ttaatgcact tttatctact gatggtaaca aaattgccga taagtatgtc
261     15601 cgcaatttac aacacagact ttatgagtgt ctctatagaa atagagatgt tgacacagac
262     15661 tttgtgaatg agttttacgc atatttgcgt aaacatttct caatgatgat actctctgac
263     15721 gatgctgttg tgtgtttcaa tagcacttat gcatctcaag gtctagtggc tagcataaag
264     15781 aactttaagt cagttcttta ttatcaaaac aatgttttta tgtctgaagc aaaatgttgg
265     15841 actgagactg accttactaa aggacctcat gaattttgct ctcaacatac aatgctagtt
266     15901 aaacagggtg atgattatgt gtaccttcct tacccagatc catcaagaat cctaggggcc
267     15961 ggctgttttg tagatgatat cgtaaaaaca gatggtacac ttatgattga acggttcgtg
268     16021 tctttagcta tagatgctta cccacttact aaacatccta atcaggagta tgctgatgtc
269     16081 tttcatttgt acttacaata cataagaaag ctacatgatg agttaacagg acacatgtta
270     16141 gacatgtatt ctgttatgct tactaatgat aacacttcaa ggtattggga acctgagttt
271     16201 tatgaggcta tgtacacacc gcatacagtc ttacaggctg ttggggcttg tgttctttgc
272     16261 aattcacaga cttcattaag atgtggtgct tgcatacgta gaccattctt atgttgtaaa
273     16321 tgctgttacg accatgtcat atcaacatca cataaattag tcttgtctgt taatccgtat
274     16381 gtttgcaatg ctccaggttg tgatgtcaca gatgtgactc aactttactt aggaggtatg
275     16441 agctattatt gtaaatcaca taaaccaccc attagttttc cattgtgtgc taatggacaa
276     16501 gtttttggtt tatataaaaa tacatgtgtt ggtagcgata atgttactga ctttaatgca
277     16561 attgcaacat gtgactggac aaatgctggt gattacattt tagctaacac ctgtactgaa
278     16621 agactcaagc tttttgcagc agaaacgctc aaagctactg aggagacatt taaactgtct
279     16681 tatggtattg ctactgtacg tgaagtgctg tctgacagag aattacatct ttcatgggaa
280     16741 gttggtaaac ctagaccacc acttaaccga aattatgtct ttactggtta tcgtgtaact
281     16801 aaaaacagta aagtacaaat aggagagtac acctttgaaa aaggtgacta tggtgatgct
282     16861 gttgtttacc gaggtacaac aacttacaaa ttaaatgttg gtgattattt tgtgctgaca
283     16921 tcacatacag taatgccatt aagtgcacct acactagtgc cacaagagca ctatgttaga
284     16981 attactggct tatacccaac actcaatatc tcagatgagt tttctagcaa tgttgcaaat
285     17041 tatcaaaagg ttggtatgca aaagtattct acactccagg gaccacctgg tactggtaag
286     17101 agtcattttg ctattggcct agctctctac tacccttctg ctcgcatagt gtatacagct
287     17161 tgctctcatg ccgctgttga tgcactatgt gagaaggcat taaaatattt gcctatagat
288     17221 aaatgtagta gaattatacc tgcacgtgct cgtgtagagt gttttgataa attcaaagtg
289     17281 aattcaacat tagaacagta tgtcttttgt actgtaaatg cattgcctga gacgacagca
290     17341 gatatagttg tctttgatga aatttcaatg gccacaaatt atgatttgag tgttgtcaat
291     17401 gccagattac gtgctaagca ctatgtgtac attggcgacc ctgctcaatt acctgcacca
292     17461 cgcacattgc taactaaggg cacactagaa ccagaatatt tcaattcagt gtgtagactt
293     17521 atgaaaacta taggtccaga catgttcctc ggaacttgtc ggcgttgtcc tgctgaaatt
294     17581 gttgacactg tgagtgcttt ggtttatgat aataagctta aagcacataa agacaaatca
295     17641 gctcaatgct ttaaaatgtt ttataagggt gttatcacgc atgatgtttc atctgcaatt
296     17701 aacaggccac aaataggcgt ggtaagagaa ttccttacac gtaaccctgc ttggagaaaa
297     17761 gctgtcttta tttcacctta taattcacag aatgctgtag cctcaaagat tttgggacta
298     17821 ccaactcaaa ctgttgattc atcacagggc tcagaatatg actatgtcat attcactcaa
299     17881 accactgaaa cagctcactc ttgtaatgta aacagattta atgttgctat taccagagca
300     17941 aaagtaggca tactttgcat aatgtctgat agagaccttt atgacaagtt gcaatttaca
301     18001 agtcttgaaa ttccacgtag gaatgtggca actttacaag ctgaaaatgt aacaggactc
302     18061 tttaaagatt gtagtaaggt aatcactggg ttacatccta cacaggcacc tacacacctc
303     18121 agtgttgaca ctaaattcaa aactgaaggt ttatgtgttg acatacctgg catacctaag
304     18181 gacatgacct atagaagact catctctatg atgggtttta aaatgaatta tcaagttaat
305     18241 ggttacccta acatgtttat cacccgcgaa gaagctataa gacatgtacg tgcatggatt
306     18301 ggcttcgatg tcgaggggtg tcatgctact agagaagctg ttggtaccaa tttaccttta
307     18361 cagctaggtt tttctacagg tgttaaccta gttgctgtac ctacaggtta tgttgataca
308     18421 cctaataata cagatttttc cagagttagt gctaaaccac cgcctggaga tcaatttaaa
309     18481 cacctcatac cacttatgta caaaggactt ccttggaatg tagtgcgtat aaagattgta
310     18541 caaatgttaa gtgacacact taaaaatctc tctgacagag tcgtatttgt cttatgggca
311     18601 catggctttg agttgacatc tatgaagtat tttgtgaaaa taggacctga gcgcacctgt
312     18661 tgtctatgtg atagacgtgc cacatgcttt tccactgctt cagacactta tgcctgttgg
313     18721 catcattcta ttggatttga ttacgtctat aatccgttta tgattgatgt tcaacaatgg
314     18781 ggttttacag gtaacctaca aagcaaccat gatctgtatt gtcaagtcca tggtaatgca
315     18841 catgtagcta gttgtgatgc aatcatgact aggtgtctag ctgtccacga gtgctttgtt
316     18901 aagcgtgttg actggactat tgaatatcct ataattggtg atgaactgaa gattaatgcg
317     18961 gcttgtagaa aggttcaaca catggttgtt aaagctgcat tattagcaga caaattccca
318     19021 gttcttcacg acattggtaa ccctaaagct attaagtgtg tacctcaagc tgatgtagaa
319     19081 tggaagttct atgatgcaca gccttgtagt gacaaagctt ataaaataga agaattattc
320     19141 tattcttatg ccacacattc tgacaaattc acagatggtg tatgcctatt ttggaattgc
321     19201 aatgtcgata gatatcctgc taattccatt gtttgtagat ttgacactag agtgctatct
322     19261 aaccttaact tgcctggttg tgatggtggc agtttgtatg taaataaaca tgcattccac
323     19321 acaccagctt ttgataaaag tgcttttgtt aatttaaaac aattaccatt tttctattac
324     19381 tctgacagtc catgtgagtc tcatggaaaa caagtagtgt cagatataga ttatgtacca
325     19441 ctaaagtctg ctacgtgtat aacacgttgc aatttaggtg gtgctgtctg tagacatcat
326     19501 gctaatgagt acagattgta tctcgatgct tataacatga tgatctcagc tggctttagc
327     19561 ttgtgggttt acaaacaatt tgatacttat aacctctgga acacttttac aagacttcag
328     19621 agtttagaaa atgtggcttt taatgttgta aataagggac actttgatgg acaacagggt
329     19681 gaagtaccag tttctatcat taataacact gtttacacaa aagttgatgg tgttgatgta
330     19741 gaattgtttg aaaataaaac aacattacct gttaatgtag catttgagct ttgggctaag
331     19801 cgcaacatta aaccagtacc agaggtgaaa atactcaata atttgggtgt ggacattgct
332     19861 gctaatactg tgatctggga ctacaaaaga gatgctccag cacatatatc tactattggt
333     19921 gtttgttcta tgactgacat agccaagaaa ccaactgaaa cgatttgtgc accactcact
334     19981 gtcttttttg atggtagagt tgatggtcaa gtagacttat ttagaaatgc ccgtaatggt
335     20041 gttcttatta cagaaggtag tgttaaaggt ttacaaccat ctgtaggtcc caaacaagct
336     20101 agtcttaatg gagtcacatt aattggagaa gccgtaaaaa cacagttcaa ttattataag
337     20161 aaagttgatg gtgttgtcca acaattacct gaaacttact ttactcagag tagaaattta
338     20221 caagaattta aacccaggag tcaaatggaa attgatttct tagaattagc tatggatgaa
339     20281 ttcattgaac ggtataaatt agaaggctat gccttcgaac atatcgttta tggagatttt
340     20341 agtcatagtc agttaggtgg tttacatcta ctgattggac tagctaaacg ttttaaggaa
341     20401 tcaccttttg aattagaaga ttttattcct atggacagta cagttaaaaa ctatttcata
342     20461 acagatgcgc aaacaggttc atctaagtgt gtgtgttctg ttattgattt attacttgat
343     20521 gattttgttg aaataataaa atcccaagat ttatctgtag tttctaaggt tgtcaaagtg
344     20581 actattgact atacagaaat ttcatttatg ctttggtgta aagatggcca tgtagaaaca
345     20641 ttttacccaa aattacaatc tagtcaagcg tggcaaccgg gtgttgctat gcctaatctt
346     20701 tacaaaatgc aaagaatgct attagaaaag tgtgaccttc aaaattatgg tgatagtgca
347     20761 acattaccta aaggcataat gatgaatgtc gcaaaatata ctcaactgtg tcaatattta
348     20821 aacacattaa cattagctgt accctataat atgagagtta tacattttgg tgctggttct
349     20881 gataaaggag ttgcaccagg tacagctgtt ttaagacagt ggttgcctac gggtacgctg
350     20941 cttgtcgatt cagatcttaa tgactttgtc tctgatgcag attcaacttt gattggtgat
351     21001 tgtgcaactg tacatacagc taataaatgg gatctcatta ttagtgatat gtacgaccct
352     21061 aagactaaaa atgttacaaa agaaaatgac tctaaagagg gttttttcac ttacatttgt
353     21121 gggtttatac aacaaaagct agctcttgga ggttccgtgg ctataaagat aacagaacat
354     21181 tcttggaatg ctgatcttta taagctcatg ggacacttcg catggtggac agcctttgtt
355     21241 actaatgtga atgcgtcatc atctgaagca tttttaattg gatgtaatta tcttggcaaa
356     21301 ccacgcgaac aaatagatgg ttatgtcatg catgcaaatt acatattttg gaggaataca
357     21361 aatccaattc agttgtcttc ctattcttta tttgacatga gtaaatttcc ccttaaatta
358     21421 aggggtactg ctgttatgtc tttaaaagaa ggtcaaatca atgatatgat tttatctctt
359     21481 cttagtaaag gtagacttat aattagagaa aacaacagag ttgttatttc tagtgatgtt
360     21541 cttgttaaca actaaacgaa caatgtttgt ttttcttgtt ttattgccac tagtctctag
361     21601 tcagtgtgtt aatcttacaa ccagaactca attaccccct gcatacacta attctttcac
362     21661 acgtggtgtt tattaccctg acaaagtttt cagatcctca gttttacatt caactcagga
363     21721 cttgttctta cctttctttt ccaatgttac ttggttccat gctatacatg tctctgggac
364     21781 caatggtact aagaggtttg ataaccctgt cctaccattt aatgatggtg tttattttgc
365     21841 ttccactgag aagtctaaca taataagagg ctggattttt ggtactactt tagattcgaa
366     21901 gacccagtcc ctacttattg ttaataacgc tactaatgtt gttattaaag tctgtgaatt
367     21961 tcaattttgt aatgatccat ttttgggtgt ttattaccac aaaaacaaca aaagttggat
368     22021 ggaaagtgag ttcagagttt attctagtgc gaataattgc acttttgaat atgtctctca
369     22081 gccttttctt atggaccttg aaggaaaaca gggtaatttc aaaaatctta gggaatttgt
370     22141 gtttaagaat attgatggtt attttaaaat atattctaag cacacgccta ttaatttagt
371     22201 gcgtgatctc cctcagggtt tttcggcttt agaaccattg gtagatttgc caataggtat
372     22261 taacatcact aggtttcaaa ctttacttgc tttacataga agttatttga ctcctggtga
373     22321 ttcttcttca ggttggacag ctggtgctgc agcttattat gtgggttatc ttcaacctag
374     22381 gacttttcta ttaaaatata atgaaaatgg aaccattaca gatgctgtag actgtgcact
375     22441 tgaccctctc tcagaaacaa agtgtacgtt gaaatccttc actgtagaaa aaggaatcta
376     22501 tcaaacttct aactttagag tccaaccaac agaatctatt gttagatttc ctaatattac
377     22561 aaacttgtgc ccttttggtg aagtttttaa cgccaccaga tttgcatctg tttatgcttg
378     22621 gaacaggaag agaatcagca actgtgttgc tgattattct gtcctatata attccgcatc
379     22681 attttccact tttaagtgtt atggagtgtc tcctactaaa ttaaatgatc tctgctttac
380     22741 taatgtctat gcagattcat ttgtaattag aggtgatgaa gtcagacaaa tcgctccagg
381     22801 gcaaactgga aagattgctg attataatta taaattacca gatgatttta caggctgcgt
382     22861 tatagcttgg aattctaaca atcttgattc taaggttggt ggtaattata attacctgta
383     22921 tagattgttt aggaagtcta atctcaaacc ttttgagaga gatatttcaa ctgaaatcta
384     22981 tcaggccggt agcacacctt gtaatggtgt tgaaggtttt aattgttact ttcctttaca
385     23041 atcatatggt ttccaaccca ctaatggtgt tggttaccaa ccatacagag tagtagtact
386     23101 ttcttttgaa cttctacatg caccagcaac tgtttgtgga cctaaaaagt ctactaattt
387     23161 ggttaaaaac aaatgtgtca atttcaactt caatggttta acaggcacag gtgttcttac
388     23221 tgagtctaac aaaaagtttc tgcctttcca acaatttggc agagacattg ctgacactac
389     23281 tgatgctgtc cgtgatccac agacacttga gattcttgac attacaccat gttcttttgg
390     23341 tggtgtcagt gttataacac caggaacaaa tacttctaac caggttgctg ttctttatca
391     23401 ggatgttaac tgcacagaag tccctgttgc tattcatgca gatcaactta ctcctacttg
392     23461 gcgtgtttat tctacaggtt ctaatgtttt tcaaacacgt gcaggctgtt taataggggc
393     23521 tgaacatgtc aacaactcat atgagtgtga catacccatt ggtgcaggta tatgcgctag
394     23581 ttatcagact cagactaatt ctcctcggcg ggcacgtagt gtagctagtc aatccatcat
395     23641 tgcctacact atgtcacttg gtgcagaaaa ttcagttgct tactctaata actctattgc
396     23701 catacccaca aattttacta ttagtgttac cacagaaatt ctaccagtgt ctatgaccaa
397     23761 gacatcagta gattgtacaa tgtacatttg tggtgattca actgaatgca gcaatctttt
398     23821 gttgcaatat ggcagttttt gtacacaatt aaaccgtgct ttaactggaa tagctgttga
399     23881 acaagacaaa aacacccaag aagtttttgc acaagtcaaa caaatttaca aaacaccacc
400     23941 aattaaagat tttggtggtt ttaatttttc acaaatatta ccagatccat caaaaccaag
401     24001 caagaggtca tttattgaag atctactttt caacaaagtg acacttgcag atgctggctt
402     24061 catcaaacaa tatggtgatt gccttggtga tattgctgct agagacctca tttgtgcaca
403     24121 aaagtttaac ggccttactg ttttgccacc tttgctcaca gatgaaatga ttgctcaata
404     24181 cacttctgca ctgttagcgg gtacaatcac ttctggttgg acctttggtg caggtgctgc
405     24241 attacaaata ccatttgcta tgcaaatggc ttataggttt aatggtattg gagttacaca
406     24301 gaatgttctc tatgagaacc aaaaattgat tgccaaccaa tttaatagtg ctattggcaa
407     24361 aattcaagac tcactttctt ccacagcaag tgcacttgga aaacttcaag atgtggtcaa
408     24421 ccaaaatgca caagctttaa acacgcttgt taaacaactt agctccaatt ttggtgcaat
409     24481 ttcaagtgtt ttaaatgata tcctttcacg tcttgacaaa gttgaggctg aagtgcaaat
410     24541 tgataggttg atcacaggca gacttcaaag tttgcagaca tatgtgactc aacaattaat
411     24601 tagagctgca gaaatcagag cttctgctaa tcttgctgct actaaaatgt cagagtgtgt
412     24661 acttggacaa tcaaaaagag ttgatttttg tggaaagggc tatcatctta tgtccttccc
413     24721 tcagtcagca cctcatggtg tagtcttctt gcatgtgact tatgtccctg cacaagaaaa
414     24781 gaacttcaca actgctcctg ccatttgtca tgatggaaaa gcacactttc ctcgtgaagg
415     24841 tgtctttgtt tcaaatggca cacactggtt tgtaacacaa aggaattttt atgaaccaca
416     24901 aatcattact acagacaaca catttgtgtc tggtaactgt gatgttgtaa taggaattgt
417     24961 caacaacaca gtttatgatc ctttgcaacc tgaattagac tcattcaagg aggagttaga
418     25021 taaatatttt aagaatcata catcaccaga tgttgattta ggtgacatct ctggcattaa
419     25081 tgcttcagtt gtaaacattc aaaaagaaat tgaccgcctc aatgaggttg ccaagaattt
420     25141 aaatgaatct ctcatcgatc tccaagaact tggaaagtat gagcagtata taaaatggcc
421     25201 atggtacatt tggctaggtt ttatagctgg cttgattgcc atagtaatgg tgacaattat
422     25261 gctttgctgt atgaccagtt gctgtagttg tctcaagggc tgttgttctt gtggatcctg
423     25321 ctgcaaattt gatgaagacg actctgagcc agtgctcaaa ggagtcaaat tacattacac
424     25381 ataaacgaac ttatggattt gtttatgaga atcttcacaa ttggaactgt aactttgaag
425     25441 caaggtgaaa tcaaggatgc tactccttca gattttgttc gcgctactgc aacgataccg
426     25501 atacaagcct cactcccttt cggatggctt attgttggcg ttgcacttct tgctgttttt
427     25561 cagagcgctt ccaaaatcat aaccctcaaa aagagatggc aactagcact ctccaagggt
428     25621 gttcactttg tttgcaactt gctgttgttg tttgtaacag tttactcaca ccttttgctc
429     25681 gttgctgctg gccttgaagc cccttttctc tatctttatg ctttagtcta cttcttgcag
430     25741 agtataaact ttgtaagaat aataatgagg ctttggcttt gctggaaatg ccgttccaaa
431     25801 aacccattac tttatgatgc caactatttt ctttgctggc atactaattg ttacgactat
432     25861 tgtatacctt acaatagtgt aacttcttca attgtcatta cttcaggtga tggcacaaca
433     25921 agtcctattt ctgaacatga ctaccagatt ggtggttata ctgaaaaatg ggaatctgga
434     25981 gtaaaagact gtgttgtatt acacagttac ttcacttcag actattacca gctgtactca
435     26041 actcaattga gtacagacac tggtgttgaa catgttacct tcttcatcta caataaaatt
436     26101 gttgatgagc ctgaagaaca tgtccaaatt cacacaatcg acggttcatc cggagttgtt
437     26161 aatccagtaa tggaaccaat ttatgatgaa ccgacgacga ctactagcgt gcctttgtaa
438     26221 gcacaagctg atgagtacga acttatgtac tcattcgttt cggaagagac aggtacgtta
439     26281 atagttaata gcgtacttct ttttcttgct ttcgtggtat tcttgctagt tacactagcc
440     26341 atccttactg cgcttcgatt gtgtgcgtac tgctgcaata ttgttaacgt gagtcttgta
441     26401 aaaccttctt tttacgttta ctctcgtgtt aaaaatctga attcttctag agttcctgat
442     26461 cttctggtct aaacgaacta aatattatat tagtttttct gtttggaact ttaattttag
443     26521 ccatggcaga ttccaacggt actattaccg ttgaagagct taaaaagctc cttgaacaat
444     26581 ggaacctagt aataggtttc ctattcctta catggatttg tcttctacaa tttgcctatg
445     26641 ccaacaggaa taggtttttg tatataatta agttaatttt cctctggctg ttatggccag
446     26701 taactttagc ttgttttgtg cttgctgctg tttacagaat aaattggatc accggtggaa
447     26761 ttgctatcgc aatggcttgt cttgtaggct tgatgtggct cagctacttc attgcttctt
448     26821 tcagactgtt tgcgcgtacg cgttccatgt ggtcattcaa tccagaaact aacattcttc
449     26881 tcaacgtgcc actccatggc actattctga ccagaccgct tctagaaagt gaactcgtaa
450     26941 tcggagctgt gatccttcgt ggacatcttc gtattgctgg acaccatcta ggacgctgtg
451     27001 acatcaagga cctgcctaaa gaaatcactg ttgctacatc acgaacgctt tcttattaca
452     27061 aattgggagc ttcgcagcgt gtagcaggtg actcaggttt tgctgcatac agtcgctaca
453     27121 ggattggcaa ctataaatta aacacagacc attccagtag cagtgacaat attgctttgc
454     27181 ttgtacagta agtgacaaca gatgtttcat ctcgttgact ttcaggttac tatagcagag
455     27241 atattactaa ttattatgag gacttttaaa gtttccattt ggaatcttga ttacatcata
456     27301 aacctcataa ttaaaaattt atctaagtca ctaactgaga ataaatattc tcaattagat
457     27361 gaagagcaac caatggagat tgattaaacg aacatgaaaa ttattctttt cttggcactg
458     27421 ataacactcg ctacttgtga gctttatcac taccaagagt gtgttagagg tacaacagta
459     27481 cttttaaaag aaccttgctc ttctggaaca tacgagggca attcaccatt tcatcctcta
460     27541 gctgataaca aatttgcact gacttgcttt agcactcaat ttgcttttgc ttgtcctgac
461     27601 ggcgtaaaac acgtctatca gttacgtgcc agatcagttt cacctaaact gttcatcaga
462     27661 caagaggaag ttcaagaact ttactctcca atttttctta ttgttgcggc aatagtgttt
463     27721 ataacacttt gcttcacact caaaagaaag acagaatgat tgaactttca ttaattgact
464     27781 tctatttgtg ctttttagcc tttctgctat tccttgtttt aattatgctt attatctttt
465     27841 ggttctcact tgaactgcaa gatcataatg aaacttgtca cgcctaaacg aacatgaaat
466     27901 ttcttgtttt cttaggaatc atcacaactg tagctgcatt tcaccaagaa tgtagtttac
467     27961 agtcatgtac tcaacatcaa ccatatgtag ttgatgaccc gtgtcctatt cacttctatt
468     28021 ctaaatggta tattagagta ggagctagaa aatcagcacc tttaattgaa ttgtgcgtgg
469     28081 atgaggctgg ttctaaatca cccattcagt acatcgatat cggtaattat acagtttcct
470     28141 gtttaccttt tacaattaat tgccaggaac ctaaattggg tagtcttgta gtgcgttgtt
471     28201 cgttctatga agacttttta gagtatcatg acgttcgtgt tgttttagat ttcatctaaa
472     28261 cgaacaaact aaaatgtctg ataatggacc ccaaaatcag cgaaatgcac cccgcattac
473     28321 gtttggtgga ccctcagatt caactggcag taaccagaat ggagaacgca gtggggcgcg
474     28381 atcaaaacaa cgtcggcccc aaggtttacc caataatact gcgtcttggt tcaccgctct
475     28441 cactcaacat ggcaaggaag accttaaatt ccctcgagga caaggcgttc caattaacac
476     28501 caatagcagt ccagatgacc aaattggcta ctaccgaaga gctaccagac gaattcgtgg
477     28561 tggtgacggt aaaatgaaag atctcagtcc aagatggtat ttctactacc taggaactgg
478     28621 gccagaagct ggacttccct atggtgctaa caaagacggc atcatatggg ttgcaactga
479     28681 gggagccttg aatacaccaa aagatcacat tggcacccgc aatcctgcta acaatgctgc
480     28741 aatcgtgcta caacttcctc aaggaacaac attgccaaaa ggcttctacg cagaagggag
481     28801 cagaggcggc agtcaagcct cttctcgttc ctcatcacgt agtcgcaaca gttcaagaaa
482     28861 ttcaactcca ggcagcagta ggggaacttc tcctgctaga atggctggca atggcggtga
483     28921 tgctgctctt gctttgctgc tgcttgacag attgaaccag cttgagagca aaatgtctgg
484     28981 taaaggccaa caacaacaag gccaaactgt cactaagaaa tctgctgctg aggcttctaa
485     29041 gaagcctcgg caaaaacgta ctgccactaa agcatacaat gtaacacaag ctttcggcag
486     29101 acgtggtcca gaacaaaccc aaggaaattt tggggaccag gaactaatca gacaaggaac
487     29161 tgattacaaa cattggccgc aaattgcaca atttgccccc agcgcttcag cgttcttcgg
488     29221 aatgtcgcgc attggcatgg aagtcacacc ttcgggaacg tggttgacct acacaggtgc
489     29281 catcaaattg gatgacaaag atccaaattt caaagatcaa gtcattttgc tgaataagca
490     29341 tattgacgca tacaaaacat tcccaccaac agagcctaaa aaggacaaaa agaagaaggc
491     29401 tgatgaaact caagccttac cgcagagaca gaagaaacag caaactgtga ctcttcttcc
492     29461 tgctgcagat ttggatgatt tctccaaaca attgcaacaa tccatgagca gtgctgactc
493     29521 aactcaggcc taaactcatg cagaccacac aaggcagatg ggctatataa acgttttcgc
494     29581 ttttccgttt acgatatata gtctactctt gtgcagaatg aattctcgta actacatagc
495     29641 acaagtagat gtagttaact ttaatctcac atagcaatct ttaatcagtg tgtaacatta
496     29701 gggaggactt gaaagagcca ccacattttc accgaggcca cgcggagtac gatcgagtgt
497     29761 acagtgaaca atgctaggga gagctgccta tatggaagag ccctaatgtg taaaattaat
498     29821 tttagtagtg ctatccccat gtgattttaa tagcttctta ggagaatgac aaaaaaaaaa
499     29881 aaaaaaaaaa aaaaaaaaaa aaa
500 """
501 for s in " \n0123456789":
502     cc = cc.replace(s, "")


  • odstraněním řádku 13 a 14 byla vyjmuta mezera
 1 sekvence = cc
 2 b = ""
 3 for x in sekvence:
 4     if x == "a":
 5         y = "00"
 6     elif x == "t":
 7         y = "01"
 8     elif x == "g":
 9         y = "10"
10     elif x == "c":
11         y = "11"
12     
13     b = b + y
14 print(b)
  • přidáním další části kódu byl řešen převod a rozdělení řádků po 120 znacích
  • přidáním mezery na začátek řetězce S = " " a přidáním mezery na konci řádku "\n " vznikly mezery na začátcích řádků pro přehlednější orientaci umístění výstupu na Wikiverzitě
1 i = 0
2 s = " "
3 for x in b:
4     i = i+1
5     if i % 120 != 0:
6         s = s + x
7     elif i % 120 == 0:
8         s = s + x + "\n "
9 print(s)

Závěr[editovat]

Celý převod genomu viru SARS-COV-2 (sekvence s označením NC_045512.2 všech 30 000 bází), řazeno bez mezer po 120 znaků, což odpovídá 60 bázím na řádek:

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110011101100100100010000010100000100001101000001010011011001111001011000110010100011001110001001000011011110011101000111
010111011011001010110110110101001110100101011110011111100110010110110010111110000111000111001011001100011101001010010101
111001111110101001100110001111100000001010010000100001101000100010111101011001111111011010010101110000111000100000000011
001100111001111100001101110010010101101111011001010101001100101001011110111000111001101101111001001110011010110101011010
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001000001000101100001000001000001000010110100101001000011000011000010010011100001100000011011001011010011100001100001000
111010110010011000101000110000011100100011000011010011010001011100000011000001011001011000101001011100001111011100000101
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011101010110100010110011000000001111001001011000000011000111000000010111100101011000011001001101100000100111001000101000
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Reference[editovat]